Molecular cloning and sequence analysis of a human untranslated Alu-containing RNA

DNA Seq. 2001 Jul;12(1):85-9. doi: 10.3109/10425170109042055.

Abstract

A cDNA, designated LNX1, has been identified by subtractive hybridization on the basis that it is expressed in normal human prostate but not in LNCaP cells. Sequence analysis revealed that it contained two Alu repetitive sequences but no long open reading frame. Hence, it belongs to a class of untranslated Alu-containing RNAs. LNX1 is expressed in most tissues. It is encoded by a single copy gene, which is localized on human chromosome 14.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alu Elements*
  • Base Sequence
  • Chromosomes, Human, Pair 14 / genetics
  • Cloning, Molecular
  • DNA, Complementary / genetics
  • Female
  • Gene Expression
  • Humans
  • Male
  • Molecular Sequence Data
  • Pregnancy
  • Tissue Distribution
  • Untranslated Regions / genetics*

Substances

  • DNA, Complementary
  • Untranslated Regions

Associated data

  • GENBANK/AF222691