Chlamydia pneumoniae exacerbates aortic inflammatory foci caused by murine cytomegalovirus infection in normocholesterolemic mice

K Burian; K Berencsi; V Endresz; Z Gyulai; T Valyi-Nagy; I Valyi-Nagy; M Bakay; Y Geng; D Virok; L Kari; R Hajnal-Papp; G Trinchieri; E Gonczol

doi:10.1128/CDLI.8.6.1263-1266.2001

Chlamydia pneumoniae exacerbates aortic inflammatory foci caused by murine cytomegalovirus infection in normocholesterolemic mice

Clin Diagn Lab Immunol. 2001 Nov;8(6):1263-6. doi: 10.1128/CDLI.8.6.1263-1266.2001.

Authors

K Burian¹, K Berencsi, V Endresz, Z Gyulai, T Valyi-Nagy, I Valyi-Nagy, M Bakay, Y Geng, D Virok, L Kari, R Hajnal-Papp, G Trinchieri, E Gonczol

Affiliation

¹ Department of Medical Microbiology, Szeged, Hungary.

Abstract

Inflammatory foci induced by murine cytomegalovirus infection in normocholesterolemic mice were present temporarily in the aortic wall, but some of these foci developed into advanced lesions that persisted late after infection. The early foci induced by virus infection were significantly exacerbated following a single inoculation with Chlamydia pneumoniae.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Aortitis / microbiology
Aortitis / pathology
Aortitis / virology*
Arteriosclerosis / immunology
Arteriosclerosis / pathology
Chlamydophila Infections / immunology*
Chlamydophila Infections / pathology
Chlamydophila Infections / virology
Chlamydophila pneumoniae*
Cholesterol / blood
Cytomegalovirus Infections / immunology*
Cytomegalovirus Infections / microbiology
Cytomegalovirus Infections / pathology
Male
Mice
Mice, Inbred BALB C
Pneumonia, Bacterial / immunology*
Pneumonia, Bacterial / pathology
Pneumonia, Bacterial / virology

Substances

Cholesterol