Abstract
A 39-year-old man with acute myeloid leukemia underwent completely matched related hematopoietic stem cell transplantation. On post-transplantation day 83 he was diagnosed as having upper gastrointestinal graft-versus-host disease (GVHD) by endoscopic examination and pathological examination of endoscopic biopsy specimens, and daily administration of 60 mg of water-soluble prednisolone and 50 mg of cyclosporine was started. After steroid therapy, the symptoms of upper gastrointestinal GVHD disappeared completely and endoscopic findings dramatically improved.
MeSH terms
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Acute Disease
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Adult
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Cyclosporine / therapeutic use
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Endoscopy, Gastrointestinal
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Gastrointestinal Diseases / drug therapy*
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Gastrointestinal Diseases / etiology*
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Gastrointestinal Diseases / pathology
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Graft vs Host Disease / drug therapy*
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Graft vs Host Disease / etiology*
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Graft vs Host Disease / pathology
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Hematopoietic Stem Cell Transplantation / adverse effects*
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Humans
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Immunosuppressive Agents / therapeutic use
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Leukemia, Myeloid / pathology
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Leukemia, Myeloid / surgery*
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Male
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Prednisolone / therapeutic use*
Substances
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Immunosuppressive Agents
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Cyclosporine
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Prednisolone