High incidence of erythromycin resistance among clinical isolates of Streptococcus agalactiae in Taiwan

Antimicrob Agents Chemother. 2001 Nov;45(11):3205-8. doi: 10.1128/AAC.45.11.3205-3208.2001.

Abstract

The in vitro susceptibilities of 266 isolates of Streptococcus agalactiae determined by the agar dilution method showed that 6% of isolates were nonsusceptible to penicillin and 46% was resistant to erythromycin. Of the erythromycin-resistant isolates, 86.3% had the macrolide-lincosamide-streptogramin (MLS) resistance phenotype (constitutive MLS, 85.5%; inducible MLS, 0.8%) and 13.7% had the M phenotype.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Clindamycin / pharmacology
  • Drug Resistance, Microbial
  • Erythromycin / pharmacology*
  • Microbial Sensitivity Tests
  • Phenotype
  • Serotyping
  • Streptococcal Infections / epidemiology*
  • Streptococcal Infections / microbiology*
  • Streptococcus agalactiae / drug effects*
  • Taiwan / epidemiology

Substances

  • Anti-Bacterial Agents
  • Clindamycin
  • Erythromycin