Spinal meningioma after treatment for Hodgkin disease. Case report

J Neurosurg. 2001 Oct;95(2 Suppl):232-5. doi: 10.3171/spi.2001.95.2.0232.

Abstract

Long-term survivors of Hodgkin disease may develop second primary tumors caused by the mutagenic effects of radio- and chemotherapy. The authors describe the case of a 35-year-old woman who presented with an unusual meningioma of the cervical spine 9 years after undergoing combined-modality treatment for Hodgkin disease. To the authors' knowledge, this is the first report of spinal meningioma as a complication of such therapy. Whereas radiation-induced intracranial meningiomas are well described in the literature, treatment-induced meningiomas of the spine have not been widely recognized.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Combined Modality Therapy / adverse effects
  • Female
  • Hodgkin Disease / therapy*
  • Humans
  • Meningioma / etiology*
  • Neoplasms, Second Primary*
  • Radiotherapy / adverse effects
  • Spinal Neoplasms / etiology*