The results of vaccination carried out in an organized group with the subunit influenza vaccine "Influvax" are presented. In the immunized group the registered morbidity level exceeded the annual morbidity level by 7-12% only against the expected epidemic rise. Respiratory diseases in this group took a mild course. The morbidity level in the control group corresponded to the predicted value and exceeded the morbidity level in the vaccinated group 4.2-fold. The conclusion was made on the effectiveness of immunoprophylaxis.