Comparative evaluation of clinical, endoscopic and morphological stomach mucosa changes dynamics was performed in 100 patients with presence and absence of HP eradication during 3 years. Improvement of clinical, endoscopic and disease morphological sings, sometimes the complete its normalization, but never worsening were observed in the most patients with HP eradication. The main pathomorphological indexes were for certain decreased after 1 year of eradication. The same indexes were not changed in the patients with still presence of HP infection. The complete normalization of stomach mucosa morphology was revealed in 28% of children during 3 years after HP eradication. New HP infection and recurrence of complains and increase of inflammatory and dystrophic stomach mucosa changes were revealed in 43% of children.