Plasticity of skeletal muscle fibres in space-flown primates

J Gravit Physiol. 1994 May;1(1):P64-6.

Abstract

Skeletal muscle atrophy and fibre type transitions were observed as a rule in rats exposed to micro- and zero-gravity, flown on boards of biosatellites and space shuttle ships. Much less is known about the spaceflight-induced muscle events in primates. The latter are animals of special interest since pattern of their onground motor activities works in ways alike to the human one, though the opportunities of studies are much wider. One of the targets of the study was to investigate the influence of spaceflight conditions on tissue morphology in monkey skeletal muscles of different functional and structural organization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biopsy
  • Glycerol-3-Phosphate Dehydrogenase (NAD+)
  • Glycerolphosphate Dehydrogenase / metabolism
  • Glycolysis
  • Macaca mulatta
  • Muscle Fibers, Fast-Twitch / physiology*
  • Muscle Fibers, Fast-Twitch / ultrastructure
  • Muscle Fibers, Slow-Twitch / physiology*
  • Muscle Fibers, Slow-Twitch / ultrastructure
  • Muscle, Skeletal / enzymology
  • Muscle, Skeletal / pathology
  • Muscle, Skeletal / physiology*
  • Muscle, Skeletal / ultrastructure
  • Muscular Atrophy / pathology
  • Muscular Atrophy / physiopathology
  • Space Flight*
  • Weightlessness*

Substances

  • Glycerolphosphate Dehydrogenase
  • Glycerol-3-Phosphate Dehydrogenase (NAD+)