(-)-Terpestacin and L-tenuazonic acid, inducers of pigment and aerial mycelium formation by Fusarium culmorum JP 15

B Schlegel; M Schmidtke; H Dörfelt; P Kleinwächter; U Gräfe

doi:10.1002/1521-4028(200107)41:3/4<179::aid-jobm179>3.0.co;2-h

(-)-Terpestacin and L-tenuazonic acid, inducers of pigment and aerial mycelium formation by Fusarium culmorum JP 15

J Basic Microbiol. 2001;41(3-4):179-83. doi: 10.1002/1521-4028(200107)41:3/4<179::aid-jobm179>3.0.co;2-h.

Authors

B Schlegel¹, M Schmidtke, H Dörfelt, P Kleinwächter, U Gräfe

Affiliation

¹ Department of Biostructure Chemistry, Hans-Knöll-Institute for Natural Products Research, Beutenbergstrasse 11, D-07745 Jena, Germany.

PMID: 11512450
DOI: 10.1002/1521-4028(200107)41:3/4<179::aid-jobm179>3.0.co;2-h

Abstract

Surface cultures of Fusarium culmorum JP15 were found to respond to extracts of other fungi by enhanced production of orange-red fusarubin pigments and formation of aerial mycelium. Two inducers from strain Ulocladium sp. HKI 0226, the new (-)-terpestacin (1) and L-tenuazonic acid (2), were isolated. 1 inhibited syncytium formation by cells infected with respiratory syncytial virus (RSV).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bridged Bicyclo Compounds / metabolism*
Culture Media
Fusarium / growth & development*
Mass Spectrometry / methods
Morphogenesis
Pigments, Biological / biosynthesis*
Respiratory Syncytial Viruses / physiology
Tenuazonic Acid / metabolism*

Substances

Bridged Bicyclo Compounds
Culture Media
Pigments, Biological
terpestacin
Tenuazonic Acid