Acute bacterial arthritis caused by group C streptococci

Semin Arthritis Rheum. 2001 Aug;31(1):43-51. doi: 10.1053/sarh.2001.21405.

Abstract

Objectives: To summarize the characteristics of and clinical experience with joint infection by group C streptococcus.

Methods: Two new cases of acute bacterial arthritis due to group C streptococci are reported, and a MEDLINE search was performed, which located 22 additional cases.

Results: Mean age (+/- standard deviation) of all 24 patients was 46 +/- 25 years, and most patients were men (75%). The species most frequently identified was Streptococcus equisimilis (12 cases). Eight patients (33%) had a general risk factor for infection, and the same percentage had some type of arthropathy. Only 3 patients had previous contact with animals. The infection was polyarticular in a third of cases, and the joint most frequently involved was the knee. The majority of patients showed a good response to the treatment with intravenous penicillin. However, 3 patients had functional sequelae, 2 more had residual radiological lesions, and 3 died.

Conclusions: Acute bacterial arthritis due to group C streptococci is a serious but uncommon entity that can affect patients without risk factors. Rapid diagnosis and treatment may improve the outcome. Semin Arthritis Rheum 31:43-51.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Aged
  • Arthritis, Infectious / drug therapy
  • Arthritis, Infectious / microbiology*
  • Arthritis, Infectious / pathology
  • Cloxacillin / administration & dosage
  • Cloxacillin / therapeutic use
  • Humans
  • Injections, Intravenous
  • Male
  • Penicillin G / administration & dosage
  • Penicillin G / therapeutic use
  • Streptococcal Infections / complications*
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / pathology
  • Streptococcus equi / growth & development
  • Streptococcus equi / isolation & purification*

Substances

  • Cloxacillin
  • Penicillin G