Quality of life of 198 patients in term for 1 to 3 years after performance of laparoscopic cholecystectomy (LCHE) was studied. The questionnaire data were estimated according to scale of Visick. Late follow-up result was excellent (Visick I) in 81 (40.9%), good (Visick II)--in 45 (22.7%), fair (Visick III)--in 53 (26.8%) and bad (Visick IV)--in 19 (9.6%) of patients. Patients with fair (Visick III) and bad (Visick IV) results were examined to reveal the cause of such outcome. The main causes of fair result were chronic disorders of gastroduodenal motor-evacuation function and of the bad result--noncorrected residual and iatrogenic traumatic pathological changes of extrahepatic biliary ducts. The quality of life estimation permits to characterize precisely the patient's health state, to choose the most rational approach to the treatment and to analyze its efficacy.