Three kinds of three dimension finite element models of edentulous mandibile and the complete denture were established to investigate the influence of artificial teeth positions to denture retention and the supporting tissue. Ten myodynamic and traditional complete dentures were constructed to compare the difference of artificial teeth positions to alveolar ridge. The results indicated: 1. The stress was not obvious different in mandible when teeth were placed over the crest of the ridge or moved lingually or buccally to the ridge in 3 mm; 2. Under occlusion force, it was beneficial for the lower supporting tissue with artificial molars being placed over the slope of mandible and beneficial for denture retention with molars teeth being placed on the crest of ridge buccally; 3. With the effects of oral muscles, the teeth on the crest of ridge buccally or lingually in 3 mm in molar and premolar regions were respectively available; 4. There were obvious difference in arch width of artificial teeth arrangement between traditional and myodynamic complete dentures, the arch was wider in myodynamic complete denture than that of traditional complete denture at molar region.