Actaeaepoxide 3-O-beta-D-xylopyranoside, a new cycloartane glycoside from the rhizomes of Actaea racemosa (Cimicifuga racemosa)

K Wende; C Mügge; K Thurow; T Schöpke; U Lindequist

doi:10.1021/np000619e

Actaeaepoxide 3-O-beta-D-xylopyranoside, a new cycloartane glycoside from the rhizomes of Actaea racemosa (Cimicifuga racemosa)

J Nat Prod. 2001 Jul;64(7):986-9. doi: 10.1021/np000619e.

Authors

K Wende¹, C Mügge, K Thurow, T Schöpke, U Lindequist

Affiliation

¹ Department of Pharmaceutical Biology, Institute of Pharmacy, Faculty of Mathematics and Natural Sciences, Ernst-Moritz-Arndt-University of Greifswald, Jahnstrasse 15a, D-17487 Greifswald, Germany.

PMID: 11473444
DOI: 10.1021/np000619e

Abstract

A new cycloartane glycoside (1) was obtained from a minor triterpene fraction of the rhizome extract of Actaea racemosa (synonym: Cimicifuga racemosa) along with a known compound, cimigenol 3-O-beta-D-xylopyranoside. The structure of 1 was elucidated as 20(S),22(R),23(R),24(S)-12beta-acetoxy-16beta:23,23alpha:24-diepoxy-3beta,22beta,25-trihydroxy-9,19-cyclolanost-7-ene 3-O-beta-D-xylopyranoside (actaeaepoxide 3-O-beta-D-xylopyranoside) on the basis of spectral and chemical evidence.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, Gas
Chromatography, High Pressure Liquid
Epoxy Compounds / chemistry
Glycosides / chemistry
Glycosides / isolation & purification*
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Roots / chemistry
Plants, Medicinal / chemistry*
Spectrometry, Mass, Electrospray Ionization
Triterpenes / chemistry
Triterpenes / isolation & purification*

Substances

Epoxy Compounds
Glycosides
Triterpenes
actaeaepoxide 3-O-xylopyranoside
cimigenol 3-O-xylopyranoside