Novel sesquiterpenoids from the roots of Phyllanthus emblica

J Nat Prod. 2001 Jul;64(7):870-3. doi: 10.1021/np010059z.

Abstract

Three novel bisabolane-type sesquiterpenoids, phyllaemblic acids B (1) and C (2) and phyllaemblicin D (3), together with two new phenolic glycosides, 2-carboxylmethylphenol 1-O-beta-D-glucopyranoside (4) and 2,6-dimethoxy-4-(2-hydroxyethyl)phenol 1-O-beta-D-glucopyranoside (5), were isolated from the roots of Phyllanthus emblica. The structures of 1-5 were established by spectral and chemical methods. The absolute stereochemistry of 1 and 2 was determined by applying the PGME method.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Euphorbiaceae / chemistry*
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Medicine, Chinese Traditional
  • Molecular Conformation
  • Molecular Structure
  • Phytotherapy
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry*
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Structure-Activity Relationship

Substances

  • 2,6-dimethoxy-4-(2-hydroxyethyl)phenol 1-O-glucopyranoside
  • 2-carboxylmethylphenol 1-O-glucopyranoside
  • Glucosides
  • Sesquiterpenes
  • phyllaemblic acid B
  • phyllaemblic acid C
  • phyllaemblicin D