[Integrin alpha-6 in cervix neck squamous cell carcinoma HPV 16/18 positive and negative]

Ginekol Pol. 2001 Apr;72(4):207-11.
[Article in Polish]

Abstract

In the present paper we study expression of alpha-6 integrin in normal paraepidermal epithelium, in CIN and in cervical invasive carcinoma HPV 16/18 positive and negative. The results suggest that alpha-6 integrin might be a marker for the evaluation of malignancy of squamous cell carcinoma. There is no correlation between the expression of alpha-6 integrin and the presence of HPV.

Publication types

  • English Abstract

MeSH terms

  • Antigens, CD / analysis*
  • Biomarkers, Tumor / analysis*
  • Carcinoma in Situ / chemistry*
  • Carcinoma in Situ / pathology
  • Carcinoma in Situ / virology
  • Carcinoma, Squamous Cell / chemistry*
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / virology
  • DNA, Viral / analysis
  • DNA-Binding Proteins*
  • Epithelium / chemistry
  • Female
  • Humans
  • Immunohistochemistry
  • Integrin alpha6
  • Oncogene Proteins, Viral / analysis
  • Papillomaviridae / isolation & purification*
  • Repressor Proteins*
  • Uterine Cervical Neoplasms / chemistry*
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / virology

Substances

  • Antigens, CD
  • Biomarkers, Tumor
  • DNA, Viral
  • DNA-Binding Proteins
  • E6 protein, Human papillomavirus type 16
  • E6 protein, Human papillomavirus type 18
  • Integrin alpha6
  • Oncogene Proteins, Viral
  • Repressor Proteins