Background: According to the concept of Partial Androgen Deficiency of the Aging Male (PADAM), testosterone supplementation becomes recommended in prevention and therapy of different disturbances especially in aging males.
Methods and results: In the group of 58 married patients with varicocele and in 85 married normozoospermic men the plasma testosterone levels were estimated and the coital activity was determined by an interview. Plasma values of male sex hormone of patients with varicocele were significantly lower (p < 0.01) than those of controls. The coital activity of both groups was not significantly different.
Conclusions: The hypothesis is presented expressing that Nature ensuring the existence of the human species produces in an over-supply not only of spermatozoids, but also of the male sexual hormones.