Images of Action Potential Propagation in Heart

News Physiol Sci. 2000 Feb:15:33-41. doi: 10.1152/physiologyonline.2000.15.1.33.

Abstract

Activation and repolarization across mammalian hearts follow complex three-dimensional pathways that are governed by fiber structure, intercellular coupling, and action potentials (APs) with spatially heterogeneous properties. Voltage-sensitive dyes and imaging techniques offer new insights on how spatiotemporal heterogeneities of APs govern propagation, repolarization, and AV node conduction and help us visualize arrhythmias with previously unattainable details.