Bladder instillation of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo

Urology. 2001 Jun;57(6 Suppl 1):111. doi: 10.1016/s0090-4295(01)01041-x.

Authors

G J Christ¹, N S Day, C Santizo, W Zhao, T Sclafani, V Karicheti, M Valcic, A Melman

Affiliation

¹ Department of Urology, Institute for Smooth Muscle Biology, Albert Einstein College of Medicine, Bronx, New York, USA.

PMID: 11378078
DOI: 10.1016/s0090-4295(01)01041-x

No abstract available

MeSH terms

Animals
DNA, Complementary / therapeutic use
Female
Genetic Therapy / methods*
Large-Conductance Calcium-Activated Potassium Channels
Muscle Contraction
Muscle, Smooth / drug effects*
Muscle, Smooth / physiopathology
Potassium Channels, Calcium-Activated / genetics
Potassium Channels, Calcium-Activated / therapeutic use*
Rats
Rats, Sprague-Dawley
Urinary Bladder / drug effects*
Urinary Bladder / physiopathology
Urinary Bladder Neck Obstruction / physiopathology
Urinary Bladder Neck Obstruction / therapy*

Substances

DNA, Complementary
Large-Conductance Calcium-Activated Potassium Channels
Potassium Channels, Calcium-Activated