Skin involvement as the first manifestation of systemic aspergillosis in patients after allogeneic hematopoietic cell transplantation

Bone Marrow Transplant. 2001 Apr;27(7):753-5. doi: 10.1038/sj.bmt.1702835.

Abstract

Skin involvement due to a systemic infection with Aspergillus species in the course of allogeneic hematopoietic cell transplantation is extremely rare. We report the clinical course of two patients with hematologic malignancies who underwent allogeneic hematopoietic cell transplantation (HCT) and developed disseminated skin involvement as the first clinical symptom of a proven systemic Aspergillus infection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aspergillosis / etiology
  • Aspergillosis / immunology
  • Aspergillosis / pathology*
  • Fatal Outcome
  • Hematologic Neoplasms / complications
  • Hematologic Neoplasms / therapy
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Immunocompromised Host / physiology
  • Male
  • Middle Aged
  • Necrosis
  • Skin Diseases / etiology*
  • Skin Diseases / microbiology
  • Skin Diseases / pathology
  • Transplantation, Homologous / adverse effects