[Directed modification of the pyrrole ring D in natural chlorins]

Bioorg Khim. 2001 Mar-Apr;27(2):141-4. doi: 10.1023/a:1011337304402.
[Article in Russian]

Abstract

Natural chlorins containing a residue of the nonesterified propionic acid in the pyrrole ring D were oxidized with 2,3-dichloro-5,6-dicyanobenzoquinone at C18 to yield exocyclic delta-lactones. The opening of the lactones in alkaline medium resulted in the corresponding 18-hydroxychlorins.

MeSH terms

  • Chlorophyll / analogs & derivatives*
  • Chlorophyll / chemistry
  • Chlorophyll A
  • Lactones / chemical synthesis
  • Magnetic Resonance Spectroscopy
  • Oxidation-Reduction
  • Photosensitizing Agents / chemical synthesis*
  • Porphyrins / chemistry*
  • Pyrroles / chemistry*
  • Spectrophotometry, Infrared
  • Stereoisomerism

Substances

  • Lactones
  • Photosensitizing Agents
  • Porphyrins
  • Pyrroles
  • Chlorophyll
  • pyropheophorbide a
  • chlorin
  • pheophorbide a
  • Chlorophyll A