[Prevalence of chronic hidden infections in a cohort of patients in substitutive treatment with methadone]

Med Clin (Barc). 2001 Mar 10;116(9):330-2. doi: 10.1016/s0025-7753(01)71817-9.
[Article in Spanish]

Abstract

Background: To analyse prevalence of hidden hepatitis B infection (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and tuberculosis infection in drug users (DU) in a maintenance programme with methadone (MPM).

Patients and method: 189 DU were tested for HBV, HCV, HIV and tuberculin test. Drug addition history and route of administration were evaluated.

Results: Prevalence of HIV, HCV, and tuberculous infection was 29.2%, 75.9% and 59.3% respectively. Intravenous route, early use of heroin and delay to enter in MPM were significatively associated with HIV and HCV infections.

Conclusions: There is a high prevalence of tuberculous and HCV infections in DU. Early access to MPM could decrease prevalence of those infections.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • HIV Infections / complications
  • HIV Infections / epidemiology*
  • Hepatitis B, Chronic / complications
  • Hepatitis B, Chronic / epidemiology*
  • Hepatitis C, Chronic / complications
  • Hepatitis C, Chronic / epidemiology*
  • Humans
  • Male
  • Methadone / therapeutic use*
  • Narcotics / therapeutic use*
  • Prevalence
  • Substance-Related Disorders / complications
  • Substance-Related Disorders / rehabilitation*
  • Tuberculosis / complications
  • Tuberculosis / epidemiology*

Substances

  • Narcotics
  • Methadone