[Cancer of the prostate: influence of nutritional factors. A new nutritional approach]

Presse Med. 2001 Mar 24;30(11):561-4.
[Article in French]

Abstract

FIBERS: A group of vegetarian subjects have been shown to have a lower risk of cancer of the prostate than a control group. But the exact role of food fiber remains to be determined because plant foods also have an antioxidant effect on their own. PLANT PRODUCTS AND EXTRACTS: A compound called PD SPEC has been showed to have antitumor effects both in vitro and in vivo. Evaluated in patients with a cancer escaping hormone control, the clinical response was a lower level of prostate specific antigen (PSA). SOYBEANS: Several studies have demonstrated the interesting properties of soybeans. No study has however been able to demonstrate the optimal dose per day. A prospective study is currently under way using a 40 g/day dose. OVERALL NUTRITIONAL APPROACH: Several studies are being conducted using a proposed diet where 15% of the total energy intake comes from fat (associated with a low saturated/unsaturated ratio), high fiber content (18 g/100 kcal) and 40 g daily soybean protein. Although large-scale studies with rigorous methodology are lacking, an overall nutritional approach could be an interesting strategy for the management of cancer of the prostate.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Clinical Trials as Topic
  • Diet
  • Diet, Vegetarian*
  • Dietary Fiber / therapeutic use
  • Drugs, Chinese Herbal*
  • Energy Intake
  • Garlic / therapeutic use
  • Genistein / pharmacology
  • Genistein / therapeutic use
  • Humans
  • Male
  • Nutritional Physiological Phenomena*
  • Phytotherapy
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plants, Medicinal
  • Prospective Studies
  • Prostate-Specific Antigen / blood
  • Prostatic Neoplasms / blood
  • Prostatic Neoplasms / drug therapy
  • Prostatic Neoplasms / prevention & control*
  • Prostatic Neoplasms / therapy*
  • Rats
  • Rats, Wistar
  • Risk Factors
  • Soybean Proteins / administration & dosage
  • Tea
  • Tumor Cells, Cultured / drug effects

Substances

  • Antineoplastic Agents
  • Antineoplastic Agents, Phytogenic
  • Dietary Fiber
  • Drugs, Chinese Herbal
  • Plant Extracts
  • Soybean Proteins
  • Tea
  • herbal preparation PC-SPES
  • Genistein
  • Prostate-Specific Antigen