Adrenal myelolipoma, which is composed of hematopoietic and adipose elements, is a rare benign tumor. Most adrenal myelolipomas are asymptomatic and are found incidentally. We report two cases of adrenal myelolipoma. One was a middle-aged woman with right flank pain. Tumor size increased 8 years later. The other patient was a 63-year-old man presenting with right flank soreness. The right adrenal tumor was found by abdominal sonography. Both of them received adrenalectomy to relieve symptoms and the pathologic results showed adrenal myelolipoma. The clinical, radiologic and pathologic characteristics of these two cases are discussed together with a review of the literature.