The role of transesophageal echocardiography in the diagnosis and management of patients with aortic perivalvular abscesses

Am J Med Sci. 2001 Feb;321(2):152-5. doi: 10.1097/00000441-200102000-00007.

Abstract

Aortic valve abscesses (AVAs) are a devastating complication of aortic valve endocarditis. Over 8 years, 25 patients were diagnosed with AVA by transesophageal echo (TEE). Management and outcomes were then analyzed. Eleven (44%) AVAs involved prosthetic valves, and 6 (24%) occurred in congenitally malformed valves. Twenty patients (80%) underwent surgical intervention; the rest were treated medically. Eleven (44%) of the patients died [6 (30%) surgery patients and all the medical patients]. Eight of 11 (73%) patients who died were culture positive for Staphylococcus aureus. All patients with congenitally malformed aortic valves underwent surgical intervention and survived. We conclude that: (1) despite advances in therapy and diagnosis, patients with AVAs have a high mortality rate; (2) prognosis with AVA is especially poor when S aureus is the infectious organism; (3) patients with AVAs in congenitally malformed valves have a great outcome with surgery; (4) patients treated medically have a very poor prognosis; earlier identification by TEE may be critical to improving survival.

Publication types

  • Clinical Conference
  • Review

MeSH terms

  • Abscess / diagnostic imaging*
  • Abscess / drug therapy
  • Abscess / mortality
  • Abscess / surgery
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Aortic Valve / abnormalities
  • Aortic Valve Insufficiency / diagnostic imaging*
  • Aortic Valve Insufficiency / drug therapy
  • Aortic Valve Insufficiency / etiology
  • Aortic Valve Insufficiency / mortality
  • Aortic Valve Insufficiency / surgery
  • Candidiasis / diagnostic imaging
  • Combined Modality Therapy
  • Disease Susceptibility
  • Echocardiography, Transesophageal*
  • Embolism / etiology
  • Endocarditis, Bacterial / diagnostic imaging*
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / mortality
  • Endocarditis, Bacterial / surgery
  • Female
  • Heart Block / etiology
  • Heart Valve Prosthesis Implantation
  • Humans
  • Male
  • Middle Aged
  • Multiple Organ Failure / etiology
  • Multiple Organ Failure / mortality
  • Prosthesis-Related Infections / diagnostic imaging
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / mortality
  • Prosthesis-Related Infections / surgery
  • Staphylococcal Infections / diagnostic imaging*
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / mortality
  • Staphylococcal Infections / surgery
  • Streptococcal Infections / diagnostic imaging
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / mortality
  • Streptococcal Infections / surgery
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents