Percutaneous localization of pulmonary nodules in five patients was performed utilizing suture-ligated embolization microcoils and CT guidance. Each localization was performed prior to video-assisted thoracoscopic wedge resection of the targeted nodules. Each suture-ligated microcoil was placed within 1.0 cm of the targeted pulmonary nodule. The attached suture served as a guide to direct accurate resection of the nodules. This technique is easily performed and provides a reliable alternative to nodule localization prior to thoracoscopic resection.