The possession of the CYP2C9*3 allele is associated with low dose requirement of acenocoumarol

Pharmacogenetics. 2000 Nov;10(8):757-60. doi: 10.1097/00008571-200011000-00010.
No abstract available

MeSH terms

  • Acenocoumarol / therapeutic use*
  • Aged
  • Alleles
  • Anticoagulants / therapeutic use*
  • Aryl Hydrocarbon Hydroxylases*
  • Cytochrome P-450 CYP2C19
  • Cytochrome P-450 CYP2C9
  • Cytochrome P-450 Enzyme System / genetics*
  • Dose-Response Relationship, Drug
  • Humans
  • Mixed Function Oxygenases / genetics
  • Steroid 16-alpha-Hydroxylase*
  • Steroid Hydroxylases / genetics*

Substances

  • Anticoagulants
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Steroid Hydroxylases
  • CYP2C9 protein, human
  • Cytochrome P-450 CYP2C9
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Steroid 16-alpha-Hydroxylase
  • Acenocoumarol