The tegument protein ppUL25 of human cytomegalovirus (CMV) is a major target antigen for the anti-CMV antibody response

J Gen Virol. 2001 Feb;82(Pt 2):335-338. doi: 10.1099/0022-1317-82-2-335.

Abstract

A viral protein of approximately 82 kDa is the only structural protein of human cytomegalovirus (CMV) that is strongly immunogenic during natural infection and the corresponding gene of which is still unknown. In this work, strong evidence is presented that this protein is the product of UL25.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Antibodies, Viral / immunology
  • Antigens, Viral / chemistry
  • Antigens, Viral / immunology*
  • Blood Donors
  • Cytomegalovirus / chemistry
  • Cytomegalovirus / immunology*
  • Female
  • Humans
  • Immune Sera / immunology
  • Immunodominant Epitopes / chemistry
  • Immunodominant Epitopes / immunology*
  • Male
  • Molecular Weight
  • Organ Transplantation
  • Pregnancy
  • Viral Proteins / chemistry
  • Viral Proteins / immunology*

Substances

  • Antibodies, Viral
  • Antigens, Viral
  • Immune Sera
  • Immunodominant Epitopes
  • UL25 protein, Cytomegalovirus
  • Viral Proteins