Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy

T Kuhlmann; A Schröter; P Dechent; F Weber; H H Rustenbeck; L Füzesi; W Brück; H Ehrenreich; J Frahm

doi:10.1136/jnnp.70.2.259

Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy

J Neurol Neurosurg Psychiatry. 2001 Feb;70(2):259-62. doi: 10.1136/jnnp.70.2.259.

Authors

T Kuhlmann¹, A Schröter, P Dechent, F Weber, H H Rustenbeck, L Füzesi, W Brück, H Ehrenreich, J Frahm

Affiliation

¹ Department of Neuropathology, Georg-August- University, Göttingen, Germany.

Abstract

Single voxel proton magnetic resonance spectroscopy (MRS) provides a rapid non-invasive fingerprint of tissue chemistry. A case history is presented in which a B cell lymphoma with antecedent demyelinating lesions of the CNS was suspected by MRS and confirmed by neuropathological examination and immunoglobulin gene rearrangement.

Publication types

Case Reports

MeSH terms

Aged
Central Nervous System Diseases / diagnosis*
Demyelinating Diseases / diagnosis*
Humans
Lymphoma, B-Cell / diagnosis*
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy*
Male
Protons

Substances

Protons