MaskerAid: a performance enhancement to RepeatMasker

Bioinformatics. 2000 Nov;16(11):1040-1. doi: 10.1093/bioinformatics/16.11.1040.

Abstract

Identifying and masking repetitive elements is usually the first step when analyzing vertebrate genomic sequence. Current repeat identification software is sensitive but slow, creating a costly bottleneck in large-scale analyses. We have developed MaskerAid, a software enhancement to RepeatMasker that increased the speed of masking more than 30-fold at the most sensitive setting.

Availability: On request from the authors (see http://sapiens.wustl.edu/MaskerAid).

Contact: maskeraid@watson.wustl.edu

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Computational Biology
  • Databases, Factual
  • Humans
  • Long Interspersed Nucleotide Elements
  • Repetitive Sequences, Nucleic Acid*
  • Sequence Alignment / statistics & numerical data*
  • Short Interspersed Nucleotide Elements
  • Software*