Clinical course and surgical treatment of macular epiretinal membranes in young subjects

Ophthalmology. 2001 Jan;108(1):23-6. doi: 10.1016/s0161-6420(00)00473-5.

Abstract

Objective: To examine the surgical and nonsurgical visual outcomes of young subjects with idiopathic macular epiretinal membranes (ERMs).

Design: Retrospective observational and noncomparative interventional case series.

Participants: Nineteen consecutive subjects (20 eyes) aged 40 years or less with an idiopathic macular ERM.

Methods: Group 1: 10 consecutive eyes were initially seen with visual acuity of 20/50 or better; 7 eyes were observed, and 3 eyes with progressive visual loss to <20/50 underwent vitrectomy and membrane peeling. Group 2: 10 consecutive eyes with presenting visual acuity of 20/60 or worse underwent vitrectomy and membrane peeling.

Main outcome measures: Visual acuity, cataract formation, ERM recurrence, operative complications.

Results: Group 1: With no surgery, visual acuity remained stable or improved in 5 of 10 eyes (50%), with a mean follow-up of 3.7 years. Three of 10 eyes (30%) had visual loss < or =20/60 develop and underwent vitrectomy. Postoperative visual acuity improved an average of 6 lines with a mean follow-up of 17.6 months. Group 2: After vitrectomy, visual acuity improved 2 or more lines in 7 of 10 eyes (70%), with a mean improvement of 4.4 lines and mean follow-up of 29.2 months. Groups 1 and 2: Three of 13 eyes (23%) that underwent vitrectomy had recurrent ERM formation.

Conclusions: Young subjects with idiopathic macular ERMs and a presenting visual acuity of 20/50 or better had a favorable visual outcome with observation. Subjects with an initial vision of 20/60 or worse, or those who had a visual decrease to < or =20/60 had significantly improved visual acuity after vitrectomy. ERM recurrence is relatively high after surgery.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Epiretinal Membrane / etiology
  • Epiretinal Membrane / surgery*
  • Female
  • Fundus Oculi
  • Humans
  • Macula Lutea / pathology
  • Macula Lutea / surgery*
  • Male
  • Recurrence
  • Retrospective Studies
  • Treatment Outcome
  • Visual Acuity
  • Vitrectomy*