Guaiane dimers and germacranolide from Artemisia caruifolia

J Nat Prod. 2000 Dec;63(12):1626-9. doi: 10.1021/np000005+.

Abstract

One new germacranolide (named caruifolin A) and three new guaiane dimers (caruifolins B-D), together with six known compounds, were isolated from the aerial parts of Artemisia caruifolia. The structures were determined by chemical and spectroscopic methods.

MeSH terms

  • Anti-HIV Agents / chemistry
  • Anti-HIV Agents / isolation & purification*
  • Anti-HIV Agents / pharmacology
  • Artemisia / chemistry*
  • Cycloheptanes / chemistry
  • Cycloheptanes / isolation & purification*
  • Cycloheptanes / pharmacology
  • Dimerization
  • HIV Protease Inhibitors / chemistry
  • HIV Protease Inhibitors / isolation & purification*
  • HIV Protease Inhibitors / pharmacology
  • HIV-1 / drug effects
  • Plants, Medicinal* / chemistry
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes / pharmacology
  • Sesquiterpenes, Guaiane*
  • Spectrum Analysis

Substances

  • Anti-HIV Agents
  • Cycloheptanes
  • HIV Protease Inhibitors
  • Sesquiterpenes
  • Sesquiterpenes, Guaiane
  • caruifolin A
  • guaiane