In vitro antifungal activity of Schizozygia coffaeoides bail. (Apocynaceae) extracts

R M Kariba; G M Siboe; S F Dossaji

doi:10.1016/s0378-8741(00)00337-8

In vitro antifungal activity of Schizozygia coffaeoides bail. (Apocynaceae) extracts

J Ethnopharmacol. 2001 Jan;74(1):41-4. doi: 10.1016/s0378-8741(00)00337-8.

Authors

R M Kariba¹, G M Siboe, S F Dossaji

Affiliation

¹ Department of Botany, University of Nairobi, PO Box 30197, Nairobi, Kenya.

PMID: 11137346
DOI: 10.1016/s0378-8741(00)00337-8

Abstract

Leaf extracts of Schizozygia coffaeoides were investigated for antifungal activity using the disc diffusion assay technique. Petroleum ether 40-60 degrees C, dichloromethane-ethyl acetate (1:1) and methanol extracts were fungitoxic to Trichophyton mentagrophytes, Microsporum gypseum, Cladosporium cucumerinum and Candida albicans. The extracts were fungistatic in action.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antifungal Agents / isolation & purification
Antifungal Agents / pharmacology*
Candida albicans / drug effects
Cladosporium / drug effects
Drug Evaluation, Preclinical
Microbial Sensitivity Tests
Microsporum / drug effects
Plant Extracts / isolation & purification
Plant Extracts / pharmacology*
Trichophyton / drug effects

Substances

Antifungal Agents
Plant Extracts