Protein structure modeling for structural genomics

R Sánchez; U Pieper; F Melo; N Eswar; M A Martí-Renom; M S Madhusudhan; N Mirković; A Sali

doi:10.1038/80776

Protein structure modeling for structural genomics

Nat Struct Biol. 2000 Nov:7 Suppl:986-90. doi: 10.1038/80776.

Authors

R Sánchez¹, U Pieper, F Melo, N Eswar, M A Martí-Renom, M S Madhusudhan, N Mirković, A Sali

Affiliation

¹ Pels Family Center for Biochemistry and Structural Biology, The Rockefeller University, New York, New York 10021, USA.

PMID: 11104007
DOI: 10.1038/80776

Abstract

The shapes of most protein sequences will be modeled based on their similarity to experimentally determined protein structures. The current role, limitations, challenges and prospects for protein structure modeling (using information about genes and genomes) are discussed in the context of structural genomics.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
Review

MeSH terms

Computer Simulation*
Computers
Databases as Topic
Genomics / methods*
Models, Molecular*
Protein Conformation
Proteins / chemistry*
Proteins / genetics

Substances

Proteins