Is there a chemical interaction between calcium phosphates and hydroxypropylmethylcellulose (HPMC) in organic/inorganic composites?

J Biomed Mater Res. 2001 Feb;54(2):247-55. doi: 10.1002/1097-4636(200102)54:2<247::aid-jbm12>3.0.co;2-g.

Abstract

Solid composites of calcium phosphates and hydroxypropylmethylcellulose (HPMC) were prepared at temperatures of 121 degrees C. Three biologically relevant calcium phosphates were studied: CaHPO(4). 2H(2)O (DCPD), calcium deficient apatite (CDA), and biphasic calcium phosphate (BCP). Properties of the solid composites obtained were studied with FTIR, X-ray diffraction, and SEM techniques. Special attention was devoted to seeking a possible chemical interaction between calcium phosphates and HPMC. No interaction was found. Thus, HPMC was proven to have no influence on chemical properties of calcium phosphates.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Calcium Phosphates / chemistry*
  • Hypromellose Derivatives
  • Methylcellulose / analogs & derivatives*
  • Methylcellulose / chemistry
  • Microscopy, Electron, Scanning
  • Spectroscopy, Fourier Transform Infrared
  • Structure-Activity Relationship
  • X-Ray Diffraction

Substances

  • Calcium Phosphates
  • Hypromellose Derivatives
  • Methylcellulose