Results of premature rupture of membranes treatment including administration of continuous amnioinfusion procedure using amniotal catheter in 18 pregnancies between 23 and 28 weeks of gestation are presented in the study. Only a few early treatment complications and high rate of clinical success in the aspect of fetal surveillance were found. Clinical evidence of intra-amniotal infection after 2-6 weeks of therapy had become cesarean section cause in most cases of the study group. Authors have observed 17 live birth (one case of placental ablation excluded) with birth weight in the range of 950-2210 g (1540 +/- 230 g) with Apgar score 5-7. In the early neonatal period 7 cases of intensive care and 2 neonatal deaths were found.