Transmission of cytomegalovirus infection through breast milk in term and preterm infants. The role of cell free milk whey and milk cells

K Hamprecht; S Witzel; J Maschmann; C P Speer; G Jahn

Transmission of cytomegalovirus infection through breast milk in term and preterm infants. The role of cell free milk whey and milk cells

Adv Exp Med Biol. 2000:478:231-9.

Authors

K Hamprecht¹, S Witzel, J Maschmann, C P Speer, G Jahn

Affiliation

¹ Department of Medical Virology and Epidemiology of Viral Diseases, University Hospital of Tübingen, Germany.

PMID: 11065076

Abstract

We investigated the reactivation of cytomegalovirus during lactation and analysed the role of human milk whey and milk cells in mother-to-child-transmission. In contrast to term infants, preterm infants may be infected symptomatically by breastfeeding. Human milk whey is the material of choice for detection of maternal DNAlactia and virolactia, whereas milk cells not necessarily have to be infected in transmitters.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cytomegalovirus / genetics
Cytomegalovirus / isolation & purification*
Cytomegalovirus Infections / prevention & control
Cytomegalovirus Infections / transmission*
DNA, Viral / isolation & purification
Electrophoresis, Agar Gel
Female
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / prevention & control
Infant, Premature, Diseases / virology*
Infectious Disease Transmission, Vertical / prevention & control*
Lactation
Milk, Human / chemistry
Milk, Human / cytology
Milk, Human / virology*
Virus Shedding

Substances

DNA, Viral