Novel inhibitors of botulinus neurotoxin "A" based on variations of the SNARE motif

Proc West Pharmacol Soc. 2000:43:71-4.

Authors

J Hayden¹, J Pires, M Hamilton, G Moore

Affiliation

¹ Department of Pharmacology and Therapeutics, University of Calgary, Alberta, Canada.

PMID: 11056961

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Botulinum Toxins, Type A / antagonists & inhibitors*
Botulinum Toxins, Type A / toxicity
Chromatography, High Pressure Liquid
Membrane Proteins / chemical synthesis
Membrane Proteins / chemistry
Membrane Proteins / pharmacology*
Molecular Sequence Data
Nerve Tissue Proteins / chemistry
Nerve Tissue Proteins / pharmacology
Peptide Library
Peptides / chemical synthesis
Peptides / pharmacology
Protein Conformation
SNARE Proteins
Synaptosomal-Associated Protein 25
Vesicular Transport Proteins*

Substances

Membrane Proteins
Nerve Tissue Proteins
Peptide Library
Peptides
SNARE Proteins
Synaptosomal-Associated Protein 25
Vesicular Transport Proteins
Botulinum Toxins, Type A