316 patients with extracranial, intracranial and intracerebral lesions of the trigeminal system were examined. Together with a neurologic observation, the examination included registration of trigeminal somatosensory, acoustic brain stem and visual evoked potentials as well as electroencephalography (including brain mapping) and magnetic resonance tomography of the brain. Etiologic factors, location of the damage and systemic pathogenetic mechanisms characteristic for the main types of both paroxysmal and nonparoxysmal facial pain were established. Peculiarities of the manifestations of trigeminal neuralgia, neuropathy and differential facial pain are discussed. A comparative analysis of peculiarities of an algesic syndrome in three forms of verified radiculopathies conditioned by the lesion of trigeminal, glossopharyngeal and cerebrospinal nerves was performed. An original classification of trigeminal facial pain is proposed.