Resistance of mice exposed to whole-body irradiation to transplanted hemopoietic cells modified with RNA preparations

V P Nikolin; S I Il'inskaya; N A Popova; E I Karakin

doi:10.1007/BF02434880

Resistance of mice exposed to whole-body irradiation to transplanted hemopoietic cells modified with RNA preparations

Bull Exp Biol Med. 2000 Jun;129(6):571-4. doi: 10.1007/BF02434880.

Authors

V P Nikolin¹, S I Il'inskaya, N A Popova, E I Karakin

Affiliation

¹ Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk.

PMID: 11022253
DOI: 10.1007/BF02434880

Abstract

The resistance of irradiated mice to bone marrow grafts treated with RNA from the liver of syngenic, allogenic, or xenogenic (rat) species was studied. Syngenic recipients developed resistance to grafts treated with allogenic RNA. The resistance to allografts increased after treatment with xenogenic RNA, whereas treatment of allo- and xenografts with syngenic RNA facilitated their take.

MeSH terms

Animals
Bone Marrow Cells / drug effects*
Bone Marrow Cells / metabolism
Bone Marrow Transplantation*
Graft Survival*
Graft vs Host Reaction
Male
Mice
Mice, Inbred A
Mice, Inbred BALB C
Mice, Inbred Strains
RNA / genetics
RNA / immunology
RNA / isolation & purification
RNA / pharmacology*
Rats
Rats, Wistar
Transplantation, Heterologous
Transplantation, Homologous
Whole-Body Irradiation*

Substances

RNA