Polymerized fluorescent liposomes incorporating lanthanide ions

B C Roy; M A Fazal; A Arruda; S Mallik; A D Campiglia

doi:10.1021/ol006357p

Polymerized fluorescent liposomes incorporating lanthanide ions

Org Lett. 2000 Oct 5;2(20):3067-70. doi: 10.1021/ol006357p.

Authors

B C Roy¹, M A Fazal, A Arruda, S Mallik, A D Campiglia

Affiliation

¹ Department of Chemistry, North Dakota State University, Fargo, North Dakota 58105, USA.

PMID: 11009347
DOI: 10.1021/ol006357p

Abstract

This paper describes the design and synthesis of a polymerizable lipid capable of complexing lanthanide ions. The lipid has been successfully incorporated into liposomes and then polymerized. Fluorescence studies indicate that the diacetylene (unpolymerized lipid) and the conjugated alkenes (after polymerization) can be used as sensitizers for the lanthanide ion.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Chelating Agents / chemical synthesis*
Fluorescent Dyes
Lipids / chemical synthesis*
Liposomes / chemical synthesis*
Spectrometry, Fluorescence
Terbium / chemistry*

Substances

Chelating Agents
Fluorescent Dyes
Lipids
Liposomes
Terbium

Grants and funding

1R15 59594-01/PHS HHS/United States