Injectable gold-induced hepatitis and neutropenia in rheumatoid arthritis

Korean J Intern Med. 2000 Jul;15(2):156-9. doi: 10.3904/kjim.2000.15.2.156.

Abstract

Gold salts have been used for many years in the treatment of rheumatoid arthritis. The common side effects are mucocutaneous reactions, but hepatotoxic reaction and isolated neutropenia are rare complications. We report a 62-year-old woman with rheumatoid arthritis who had developed hepatitis and neutropenia simultaneously after receiving 137.5 mg of sodium aurothiomalate.

Publication types

  • Case Reports

MeSH terms

  • Antirheumatic Agents / adverse effects*
  • Arthritis, Rheumatoid / drug therapy*
  • Chemical and Drug Induced Liver Injury / etiology*
  • Female
  • Gold Sodium Thiomalate / adverse effects*
  • Humans
  • Injections
  • Middle Aged
  • Neutropenia / chemically induced*

Substances

  • Antirheumatic Agents
  • Gold Sodium Thiomalate