Abstract
The synthetic potentialities of cerium(III) chloride are demonstrated by the synthesis of a nine-membered ring heterocycle component of Griseoviridin (3) in optically active form. The key step involves the stereospecific formation of the alpha-carbalkoxy alkenyl sulfide moiety using a combination system of cerium(III) chloride heptahydrate and sodium iodide.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / chemistry*
-
Cerium / chemistry
-
Heterocyclic Compounds / chemical synthesis*
-
Heterocyclic Compounds / chemistry
-
Magnetic Resonance Spectroscopy
-
Peptides*
-
Sodium Iodide / chemistry
-
Stereoisomerism
-
Streptomyces / chemistry*
-
Sulfides / chemical synthesis*
-
Sulfides / chemistry
-
Virginiamycin / chemical synthesis*
-
Virginiamycin / chemistry
Substances
-
Anti-Bacterial Agents
-
Heterocyclic Compounds
-
Peptides
-
Sulfides
-
Virginiamycin
-
Cerium
-
griseoviridin
-
Sodium Iodide
-
cerous chloride