[Hemodynamic effects of spinal anesthesia with 2% lidocaine in comparison to 0.5% isobaric bupivacaine]

Anaesthesist. 2000 Jun;49(6):517-22. doi: 10.1007/s001010070092.
[Article in German]

Abstract

Background: Our study compared the haemodynamic changes after spinal anesthesia with 2% lignocaine and 0.5% plain bupivacaine.

Methods: A controlled, randomized trial was performed on 30 patients scheduled for arthroscopic knee surgery. 2% lignocaine and 0.5% plain bupivacaine were used for spinal anaesthesia. We measured cardiac output (electrical bioimpedance cardiography), blood pressure and development of sensory blockade before and for 25 minutes after spinal anaesthesia.

Results: In patients developing a sensory block below T6 there were no differences between both anaesthetics in haemodynamic parameters. But in patients developing a sensory block at or above T6 there was a greater drop in mean arterial pressure and cardiac output and a faster decrease in heart rate for bupivacaine compared to patients receiving Lignocaine.

Conclusion: In patients developing a sensory block at or above the T6 dermatome, the decrease in cardiac output and mean arterial pressure in the first 25 min after spinal anaesthesia is smaller when 2% lignocaine rather than 0.5% bupivacaine is used for blockade.

Publication types

  • Clinical Trial
  • Comparative Study
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Algorithms
  • Anesthesia, Spinal* / adverse effects
  • Anesthetics, Local* / administration & dosage
  • Arthroscopy
  • Blood Pressure / drug effects
  • Bupivacaine* / administration & dosage
  • Bupivacaine* / adverse effects
  • Female
  • Heart Rate / drug effects
  • Hemodynamics / drug effects*
  • Humans
  • Knee / surgery
  • Lidocaine* / administration & dosage
  • Lidocaine* / adverse effects
  • Male

Substances

  • Anesthetics, Local
  • Lidocaine
  • Bupivacaine