Antimicrobial constituents of the leaves of Acalypha wilkesiana and Aacalypha hispida

Phytother Res. 2000 Aug;14(5):371-4. doi: 10.1002/1099-1573(200008)14:5<371::aid-ptr625>3.0.co;2-f.

Abstract

An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside were also isolated from the inactive fraction of A. hispida. The structures were established by permethylation, 2D - NMR ((1)H and (13)C) and MS data.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Euphorbiaceae / chemistry*
  • Glucosides / chemistry
  • Humans
  • Hydrolyzable Tannins*
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Tannins*

Substances

  • Anti-Bacterial Agents
  • Glucosides
  • Hydrolyzable Tannins
  • Plant Extracts
  • Tannins
  • Geraniin
  • corilagin