Abstract
An activity directed fractionation of a 50% aqueous ethanol extract of A. wilkesiana and A. hispida leaves resulted in the isolation of gallic acid, corilagin and geraniin as the compounds responsible for the observed antimicrobial activity. Quercetin 3-O-rutinoside and kaempferol 3-O-rutinoside were also isolated from the inactive fraction of A. hispida. The structures were established by permethylation, 2D - NMR ((1)H and (13)C) and MS data.
Copyright 2000 John Wiley & Sons, Ltd.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology*
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Euphorbiaceae / chemistry*
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Glucosides / chemistry
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Humans
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Hydrolyzable Tannins*
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Magnetic Resonance Spectroscopy
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Microbial Sensitivity Tests
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Plant Extracts / chemistry
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Plant Extracts / pharmacology
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Plant Leaves / chemistry
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Plants, Medicinal / chemistry*
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Tannins*
Substances
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Anti-Bacterial Agents
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Glucosides
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Hydrolyzable Tannins
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Plant Extracts
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Tannins
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Geraniin
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corilagin