Objective: To study the effect of arterial infusion chemotherapy in patients with carcinoma of urinary bladder.
Methods: Eleven patients with advanced or moderately advanced cancer of the urinary bladder (10 transitional cell carcinoma, 1 squamous-cell carcinoma) who were for various reasons not suitable for surgical treatment were treated by arterial infusion chemotherapy according to Seldinger's percutaneous approach.
Results: The treatment results were satisfactory with an overall response rate of 90.9% (CR = 2, PR = 8). The average survival time of the 11 patients was 26.2 +/- 13.1 months. The 1-year survival rate was 81.8%. Side effects were mild.
Conclusion: Arterial infusion chemotherapy is of use in patients with advanced or moderately advanced bladder cancer.