Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana

N M Kim; J Kim; H Y Chung; J S Choi

doi:10.1007/BF02976451

Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana

Arch Pharm Res. 2000 Jun;23(3):237-9. doi: 10.1007/BF02976451.

Authors

N M Kim¹, J Kim, H Y Chung, J S Choi

Affiliation

¹ Faculty of Food Science and Biotechnology, Pukyong National University, Pusan, Korea.

PMID: 10896054
DOI: 10.1007/BF02976451

Abstract

The antioxidant activity of Artemisia montana was determined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and inhibitory activity against free radical generation of hepatocytes (AC2F). The methanol extract of A. montana showed strong radical scavenging activity at a concentration of 10.1 microg/ml, and thus fractionated by solvent extraction. Esculetin and luteolin 7-O-rutinoside (scolymoside) were isolated as the active principles from the EtOAc and Interphase fractions, respectively. The antioxidant activity of these compounds were comparable to that of L-ascorbic acid.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antioxidants / isolation & purification*
Artemisia / chemistry*
Flavonoids*
Hesperidin / analogs & derivatives*
Hesperidin / isolation & purification
Luteolin*
Plants, Medicinal*
Umbelliferones / isolation & purification*

Substances

Antioxidants
Flavonoids
Umbelliferones
veronicastroside
Hesperidin
Luteolin
esculetin