A severe clinical phenotype results from the co-inheritance of type 2 susceptibility genes and a hepatocyte nuclear factor-1alpha mutation

Diabetes Care. 2000 Mar;23(3):424-5. doi: 10.2337/diacare.23.3.424.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Amino Acid Substitution
  • C-Peptide / blood
  • DNA-Binding Proteins / genetics
  • Diabetes Mellitus, Type 2 / genetics*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Female
  • Genetic Predisposition to Disease
  • Glycated Hemoglobin / analysis
  • Hepatocyte Nuclear Factor 1
  • Hepatocyte Nuclear Factor 1-alpha
  • Hepatocyte Nuclear Factor 1-beta
  • Humans
  • Male
  • Nuclear Proteins*
  • Pedigree
  • Phenotype
  • Point Mutation*
  • Transcription Factors / genetics*

Substances

  • C-Peptide
  • DNA-Binding Proteins
  • Glycated Hemoglobin A
  • HNF1A protein, human
  • HNF1B protein, human
  • Hepatocyte Nuclear Factor 1-alpha
  • Nuclear Proteins
  • Transcription Factors
  • Hepatocyte Nuclear Factor 1
  • Hepatocyte Nuclear Factor 1-beta