Carbamazepine-associated severe left ventricular dysfunction

Abstract

Introduction: The cardiovascular effects of carbamazepine are well-known but left ventricular dysfunction is rarely reported.

Case report: We describe 2 cases of severe carbamazepine-associated left ventricular dysfunction during massive self intoxications in young patients without preexistent cardiac disease. We compare our cases to the available literature and discuss the mechanisms implied in the development of left ventricular dysfunction following carbamazepine overdose. Bedside echocardiography was useful in both diagnosis and treatment.