Thonningianins A and B, new antioxidants from the African medicinal herb Thonningia sanguinea

J Nat Prod. 2000 May;63(5):676-9. doi: 10.1021/np990396w.

Abstract

Two new ellagitannins, thonningianins A (1) and B (2), have been isolated from the African medicinal herb Thonningia sanguinea and their structures elucidated by interpretation of spectroscopic data. Both 1 and 2 showed strong free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) as shown by ESR analysis.

MeSH terms

  • Africa
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology
  • Bepridil / analogs & derivatives
  • Bepridil / chemistry
  • Biphenyl Compounds
  • Free Radical Scavengers / isolation & purification
  • Free Radical Scavengers / pharmacology
  • Free Radicals / chemistry
  • Hydrolyzable Tannins*
  • Magnetic Resonance Spectroscopy
  • Picrates*
  • Plants, Medicinal / chemistry*
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet
  • Tannins / isolation & purification*
  • Tannins / pharmacology

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Free Radicals
  • Hydrolyzable Tannins
  • Picrates
  • Tannins
  • thonningianin A
  • thonningianin B
  • Bepridil
  • 1,1-diphenyl-2-picrylhydrazyl