Computerization of national and international space research projects, real-time data management, improvement of the quality of medical support to space crew through more extensive use of video, audio and telemetric information put in the forefront the necessity to integrate individual experts and agencies in a single network. Described is the structure of the operative network mounted at the Russian Federation State Research Center--Institute of Biomedical Problems. The authors discuss issues related to networking participants in medical support of manned missions, and a biomedical data exchange format. Developed was a prototype of an on-line Web-server. Prospect for advancement of the informational network is outlined.